A 1280-Channel Neural Microelectrode Array With Complementary Wedge-Shaped 3D Assembly Interfaces

IEEE Sensors Journal(2024)

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摘要
This paper presents a novel 1280-channel three-dimensional neural microelectrode array with a complementary wedge-shaped interface. The microelectrode array consists of five 256-channel neural microelectrode chips, which are precisely stacked in three dimensions. The bonding interface between the MEMS neural microelectrode and the FPC (Flexible Printed Circuit) comprises a set of complementary wedge-shaped bonding interfaces that exhibit mirror symmetry to each other. These interfaces are encapsulated together to form a complete sensor using the ACF (Anisotropic Conductive Film) thermocompression bonding process. This bonding interface eliminates the need for any post-processing on the bonding pads, ensuring excellent consistency and achieving 100% bonding efficiency, while facilitating high-density microelectrode integration. The neural microelectrode chip adopts a composite metal layer structural design, which integrates 256 recording microelectrodes in a 1.33 mm 2 area. This design reduces the width of the needle beam while maintaining the density of the recording electrodes. Characterized by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry, microelectrodes modified with electroplated gold exhibited a significant reduction in AC impedance from 1 MΩ to 10 KΩ at 1KHz, demonstrating enhanced capacitive properties with improved charge storage capacity and charge transfer efficiency.
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关键词
Neural microelectrode arrays,MEMS,High-density,ACF bonding,3D assembly,Brain-computer interface
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