A Case of Pan-TRK Positive Dermatofibrosarcoma Protuberans Located on the Nose

Dermatofibrosarcoma protuberans (DFSP) is a rare and infiltrative soft tissue tumor. Our report details a distinctive case of DFSP with pan-TRK positivity in the right nasal dorsum of a 46-year-old female. Histological analysis identified NTRK fusion gene involvement in this patient, detectable through pan-TRK immunostaining. The case underscores the significance of comprehensive management for pan-TRKpositive DFSP in challenging facial locations, indicating the potential efficacy of TRK inhibitors.