Doppler holography for ophthalmology
arxiv(2024)
摘要
A comprehensive assessment of retinal health demands reliable and precise
methods to measure localized blood perfusion. Despite considerable advancements
in imaging techniques, such as indocyanine green and fluorescein angiography,
along with optical coherence tomography angiography, their capacity to monitor
blood flow dynamics across the cardiac cycle faces significant limitations. For
more effective care of those with ocular conditions, innovating new approaches
is paramount. Doppler holography, an emerging non-invasive optical imaging
technique, meets this challenge by offering high temporal resolution imaging of
retinal and choroidal blood flow. Now a burgeoning interdisciplinary research
field, Doppler holography intertwines functional optical imaging system design,
high-performance computing, and clinical investigation. Through collaborative
efforts among universities, industry partners, and ophthalmic clinics, a
network for its advancement and application is taking shape. This endeavor
promises to propel the discovery of novel functional biomarkers, transforming
the diagnosis and treatment of retinal diseases, refining disease severity
categorization, and enhancing therapeutic monitoring-ultimately leading to
improved healthcare outcomes.
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