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Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable in Vivo Studies: Discovery of TDI-11055

Mayako Michino,Tanweer A. Khan,Michael W. Miller,Yoshiyuki Fukase,Jeremie Vendome,Carolina Adura,J. Fraser Glickman,Yiman Liu,Liling Wan,C. David Allis,Andrew W. Stamford,Peter T. Meinke,Louis M. Renzetti,Stacia Kargman,Nigel J. Liverton,David J. Huggins

ACS Medicinal Chemistry Letters（2024）

Cited 1|Views22

Key words

epigenetics,ENL YEATS inhibitor,leukemia

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