Genetic variation drives differences in obesity-related gene regulation
Trends in Genetics(2024)
摘要
Heikkinen and colleagues recently demonstrated that genetic variation, rather than dietary changes, governs gene regulation in liver. This finding highlights the impact of noncoding variants on chromatin accessibility, histone modifications, transcription factor binding, and gene expression and has implications for future research directions in understanding the genetic basis of disease.
更多查看译文
关键词
genetics,genetic variation,gene regulation,GWAS,epigenome,chromatin
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要