GARDskin Dose-Response Assay and Its Application in Conducting Quantitative Risk Assessment (QRA) for Fragrance Materials Using a Next Generation Risk Assessment (NGRA) Framework

Shashikiran Donthamsetty,Andy Forreryd,Paul Sterchele, Xiao Huang,Robin Gradin,Henrik Johansson,Ulrika Mattson,Isabelle Lee,Anne Marie Api,Gregory Ladics

REGULATORY TOXICOLOGY AND PHARMACOLOGY（2024）

引用 3|浏览14

关键词

QRA (Quantitative Risk Assesment),Dermal sensitization,Fragrance materials,Next Generation Risk Assesment (NGRA),GARD assay,No Expected Sensitization Induction Level (NESIL),New Approach Methodologies (NAMs),OECD 442E

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