Phytochemical Analysis and In Vitro Assessment of Extracts of Rhodobryum roseum for Antioxidant, Antibacterial and Anti-Inflammatory Activities

The antibacterial, antioxidant and anti-inflammatory potential of Rhodobryum roseum extracts in organic solvents was investigated. The highest contents of total phenols, flavonoids, and antioxidants have been found in methanolic extract. Escherichia coli and Listeria monocytogenes were sensitive to the extracts, while Bacillus subtilis and Klebsiella pneumoniae were resistant. Anti-inflammatory potential of methanolic extract was assessed in the LPS-induced RAW 264.7 macrophage cell lines. The GC-MS of methanolic extract showed the predominance of phenolic acids, fatty acids and phytosterols, while terpenoids and flavonoids were identified by LC-MS analysis. FTIR confirmed the presence of O-H, C-H, C-N, C-F and SCN functional groups.