Metal-Catalyzed C–N Bond Forming Reaction Selection and Process Development for the Manufacture of AZD7594

Gulsevim Aydin, Matthew Ball, Thomas George Bishop, Matthew Burns,Andrew D. Campbell,Robert J. Cox,Kuangchu Dai, David Dave,Heidi Fisk, Laura Hamilton,Claire Heffernan, Jean-Marc Henry,Stephen W. Holman,Martin F. Jones,Gary Noonan,Bharti Patel, David Streather,Simone Tomasi

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

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process design,reaction selection,aziridiniumring opening,amidation,Buchwald-Hartwig

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