Current progress in glass-based nanochannels

Glass-based nanochannels have become powerful tools for chemical and biological sensing due to their advantages of easy preparation, flexible modification, and high sensitivity. Lately, research on ion transport behaviors in glass-based nanochannels and their applications in nanofluidic iontronics has gradually become a focus, including various ion transport behaviors such as resistive-pulse, ion rectification, ionic current memory, etc. In this review, we summarize the progress of manufacturing methods for glass-based nanochannels and discuss several typical ion transport behaviors of glass-based nanochannels, as well as the main application scenarios of glass-based nanochannels in terms of biosensing, detection, and neuromorphic functions. The enormous assistance of artificial intelligence in the standardized manufacturing process of glass-based nanochannels was anticipated, and the potential development of glass-based nanochannels in achieving neuromorphic functions was expected.