Photodynamic therapy combined with antifungal drugs against kerion: A report of six cases and literature review

Xiaoli Chen, Yujia Liang, Ziyu Guo, Ruiye Huang, Wenai Zheng,Weiwei Wu, Wen Li

Photodiagnosis and Photodynamic Therapy(2024)

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摘要
Kerion, a severe manifestation of tinea capitis caused by dermatophytes, is a fungal skin disease primarily affecting children. This report discusses six cases of pediatric kerion that were successfully treated with a combination of photodynamic therapy (PDT) and antifungal agents. Additionally, we conducted a literature review, identifying and analyzing six published reports on kerion and tinea capitis. The characteristics and efficacies of these cases are summarized. In summary, early combination therapy and proactive pre-treatment interventions proved effective in maximizing therapeutic outcomes, reducing disease duration and minimizing adverse reactions such as cicatricial alopecia. This approach has emerged as a favorable choice for the treatment of kerion.
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关键词
kerion,photodynamic therapy,aminolevulinic acid,antifungal drugs
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