Gene expression of cytokines and prostaglandin metabolism-related proteins in eosinophilic otitis media

Aiko Oka,Masahiro Takahashi,Wataru Nishimura, Shogo Oyamada,Shinichiro Oka,Satoshi Iwasaki,Kengo Kanai,Mitsuhiro Okano

Journal of Allergy and Clinical Immunology: Global（2024）

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摘要

The objective of this study was to investigate the levels of gene expression in the middle ear mucosa of 2 patients diagnosed with eosinophilic otitis media. One patient with severe hearing loss showed high expression levels of genes encoding IL-5 and IL-33 receptors.

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关键词

Eosinophilic otitis media,type 2 inflammation,gene expression,severity,pathogenesis

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