Assessing Bilateral Neurovascular Bundles Function with Pulsed Wave Doppler Ultrasound: Implications for Reducing Erectile Dysfunction Following Prostate Radiotherapy
arxiv(2024)
摘要
This study aims to evaluate the functional status of bilateral neurovascular
bundles (NVBs) using pulsed wave Doppler ultrasound in patients undergoing
prostate radiotherapy (RT). Sixty-two patients (mean age: 66.1 +/- 7.2 years)
underwent transrectal ultrasound scan using a conventional ultrasound scanner,
a 7.5 MHz bi-plane probe and a mechanical stepper. The ultrasound protocol
comprised 3 steps: 1) 3D B-mode scans of the entire prostate, 2) localization
of NVBs using color flow Doppler imaging, and 3) measurement of NVB function
using pulsed wave Doppler. Five pulsed Doppler waveform features were
extracted: peak systolic velocity (PSV), end-diastolic velocity (EDV), mean
velocity (Vm), resistive index (RI), and pulsatile index (PI). In summary, this
study presents a Doppler evaluation of NVBs in patients undergoing prostate RT.
It highlights substantial differences in Doppler ultrasound waveform features
between bilateral NVBs. The proposed ultrasound method may prove valuable as
clinicians strive to deliver NVB-sparing RT to preserve sexual function
effectively and enhance patients' overall well-being.
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