Cocrystals of a coumarin derivative: an efficient approach towards anti-leishmanial cocrystals against MIL-resistant Leishmania tropica

This study demonstrates the synthesis of non-cytotoxic active candidates (co-crystals) of coumarin-3-carb­oxy­lic acid with various coformers to target the MIL-resistant Leishmania tropica. These promising anti-leishmanial results indicate the importance of crystal engineering by highlighting that manipulation of supramolecular architecture in the solid state can impact the biological response.