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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Intravenous Dose of SHR-1707 in Healthy Adult Subjects: Two Randomized, Double-Blind, Single-Ascending-dose, Phase 1 Studies

Yaru Yang, Hongyan Qiu,Yuru Fan,Qin Zhang,Huiling Qin,Juan Wu, Xuan Zhang,Yueyue Liu,Renpeng Zhou,Qian Zhang, Zi Ye, Jingyue Ma, Ye Xu,Sheng Feng, Yue Fei,Na Li, Xiaojing Cui, Fangli Dong,Quanren Wang,Kai Shen,Sepehr Shakib, Jasmine Williams,Wei Hu

ALZHEIMERS RESEARCH & THERAPY（2024）

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Key words
Alzheimer’s disease,anti-Aβ monoclonal antibody,Pharmacokinetics,Pharmacodynamics,Clinical trial
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