The Effects of a Peptide Complex Cream for Improving Skin Photoaging

Bioactive peptides are different peptides composed of natural amino acids in different compositions and arrangements. They are now widely used in skin care products, but there are few studies on anti-photoaging. This article aims to investigate the efficacy of a peptide complex cream in the treatment of skin photoaging. 80 female subjects were recruited and assigned to 2 groups (40 in each group) based on a randomized, double-blind, placebo-controlled, parallel-group protocol, and were topically treated with either a peptide complex cream or a base cream. Subjective assessment was done by a physician and a non-invasive skin examination was performed at weeks 0, 2, 4, 6, 8 during the treatment and then again 4 weeks after the treatment was complete. The results showed that there was no significant improvement in facial wrinkles and color spots in the peptide complex cream group, but there was significant facial improvement (P <.05) in both the Dermoscopy Photoaging Scale (DPAS) scores and with acne. The peptide complex cream can safely and effectively improve some skin photoaging symptoms, but the effect on wrinkles and color spots is not obvious in the short term.