Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media

Zhizhou Luo, Ruonan Wang, Xiaoxia Deng,Tianxiang Chen,Xuehua Ma,Yujie Zhang,Changyong Gao,Aiguo Wu

NANOSCALE(2024)

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摘要
We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop. The efficient propulsion of MOS/Pt nanomotors in hydrogen peroxide ear-cleaning drops significantly improves their binding efficiency with Staphylococcus aureus and enhances their antibacterial efficacy. We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop.
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