The Amager Project IV: suicidal behavior and aftercare: real world data (RWD) from a prospective observational project

August G. Wang, Titia Lahoz, Marianne Hvid, Heidi K. Grufstedt, Lene M. Jorgensen

NORDIC JOURNAL OF PSYCHIATRY(2024)

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摘要
BackgroundIn an RCT study, OPAC (outreach, problem solving, adherence, continuity) approach to aftercare after suicide attempts had an effect. The present study used the OPAC method in a clinical setting on Amager Copenhagen to patients after suicide attempt (Group 1) and patients with suicide ideation (Group 2) in a real-world data (RWD) study.AimTo study whether the OPAC method could provide real world evidence (RWE) for results from the RCT study and long-time prospects.MethodThis RWD study included 506 patients and followed them for 5 years. Kaplan-Meyer showed 5 years results. Risk factors for 5 years were calculated.Results206 males (mean age 37.9) and 300 females (mean age 35.2) participated. A decline in survival accelerated after 3 years. After a 2-year follow-up, Group 1 had an attempted suicide rate of 12,2% and Group 2 5,4%. After 5 years the numbers were 18% and 10%. There were 3 completed suicides. Risk factors were: earlier suicide attempts, one or both parents or they themselves were alcohol/drug abusers, and a poor social network. Group 1 showed the same result as the intervention group in our earlier RCT study. Group 2 did better. Both groups did better than the control group from our RCT study.ConclusionThe OPAC effect was translated into the daily clinic. Risk factors were previous suicide attempts, alcohol and drug abuse and poor social networks. More specific therapy is needed for some patients to prevent relapse. Focus on enhancing a sense of belongingness and/or treating substance abuse.
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关键词
Suicide,prevention,RCT study,real-world data (RWD),suicide risk factors
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