Development and Internal Validation of a Novel Nomogram Predicting the Outcome of Salvage Radiation Therapy for Biochemical Recurrence after Radical Prostatectomy in Patients without Metastases on Restaging Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography

Dennie Meijer,Pim J. van Leeuwen,Wietse S.C. Eppinga,Ben G.L. Vanneste,Philip Meijnen,Laurien A. Daniels,Roderick C.N. van den Bergh, Anne P. Lont,Yves J.L. Bodar,Rosemarijn H. Ettema, Katelijne C.C. de Bie, Frederik H.K. Oudshoorn,Jakko A. Nieuwenhuijzen,Henk G. van der Poel,Maarten L. Donswijk, Martijn W. Heymans,Daniela E. Oprea-Lager,Eva E. Schaake,André N. Vis

European Urology Open Science（2024）

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摘要

We developed a novel nomogram for predicting outcomes of salvage radiation therapy (sRT) after prostate-specific membrane antigen positron emission tomography/computed tomography for patients with biochemical recurrence of prostate cancer after radical prostatectomy. This nomogram may facilitate better counseling of patients regarding early oncological outcomes after sRT. Patients with high risk of developing biochemical progression may be candidates for more extensive treatment.

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关键词

Salvage radiation therapy,Prostate cancer,Prostate-specific membrane antigen imaging,Positron emission tomography/computed tomography,Nomograms

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