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Early Process Development of Two Vanin-1 Inhibitors: Solid Form Challenges and Control of Ambident Reactivity

Christophe Allais,Agustin Casimiro-Garcia,Amelie Dion, Andrew J. Jensen,Nandell Keene, Rajesh Kumar,Bryan Li,Manjinder S. Lall,J. Christopher Mcwilliams, Geoffrey P. F. Wood,Stephen W. Wright,Shu Yu

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

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Key words
vanin-1 inhibitors,solid form,amorphous API,amide bond formation,SNAr
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