Synthesis and Characterization of Silver Nanoparticles Conjugated with Triazole-N-acetamide Thiazole Derivatives for Selective Detection of Cymoxanil in Complex Samples

Cymoxanil (CYM) is one of the most important fungicides for various vegetables and fruits. However, its routine detection is still expensive due to high-cost equipment. In this context, the silver nanoparticle-based colorimetric probe was synthesized using triazole-N-acetamide thiazole (TAT) derivative as a stabilizer. The triazole-N- acetamide thiazole (TAT) derivative functionalized silver nanoparticles (TAT-AgNPs) were used as a probe for selective, efficient, rapid and quantitative determination of CYM in tap and river water. The characterization of TAT-AgNPs was accomplished through UV-visible, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Zetasizer analysis. Highly sensitive surface plasmonic resonance band at 400 nm indicated complete reduction of Ag+ by using 1 : 15 (v/v) (TAT: AgNO3). The limit of detection (LOD), which corresponds to signal-to-noise ratio 3, is 0.013 mu mol L-1, showed a linear response as a function of CYM concentration from 1 to 100 mu M. Furthermore, the probe shows good selectivity when exposed to a series of interfering pesticides. TAT-AgNPs were also spiked with blood plasma and the effects of relevant interfering studies were evaluated. The nanosensor detects the CYM tap water and river water samples. It confirmed that nanosensor can detect CYM in biological and environmental samples. Cymoxanil is one of the most important fungicides for various vegetables and fruits. In this context, the silver nanoparticle-based sensor was fabricated using triazole-N-acetamide thiazole (TAT) derivative as a stabilizer. The triazole-N-acetamide thiazole (TAT) derivative functionalized silver nanoparticles (TAT-AgNPs) were used as a sensor for the detection of Cymoxanil. The characterization of TAT-AgNPs was accomplished through UV-visible, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Zetasizer analysis. The limit detection level of Cymoxanil using the sensor was at 0.013 mu mol L-1.Thenanosensor can detect the Cymoxanil tap water, river water and blood samples. image