reduced Cytokine Release Syndrome and improved Outcomes with Earlier Immunosuppressive Therapy in Haploidentical Stem Cell Transplant

•Earlier immunosuppression associated with decreased rates of cytokine release syndrome•Modified post-transplant cyclophosphamide regimen associated with reduced risk of graft-versus-host disease•Haplo-CRS associated with decreased graft-versus-host disease-free, relapse-free survival•More research needed to determine best timing of haplo-transplant immunosuppression