The cumulative effects of stigma-related stress: Chronic stigma-related stress exposure exacerbates daily associations between enacted stigma and anxious/depressed affect

•Individuals with chronic stigma exposure experienced higher anxious/depressed affect on days when they had daily stigma experiences.•These individuals continued to experience increases in anxious/depressed affect later in the day following stigma experiences.•Individuals with chronic stigma exposure experienced lower perceived coping efficacy on days when they had daily stigma experiences.•The daily effects of stigma on anxious/depressed affect persisted for longer among individuals with chronic stigma exposure.•Chronic stigma exposure did not moderate daily effects of general stressors.