How Does Patient-centered Communication Influence Patient Trust?: The Roles of Patient Participation and Patient Preference

•The study titled "How Does Patient-Centered Communication Influence Patient Trust? The Roles of Patient Participation and Patient Preference" conducted a cross-sectional survey with 217 cancer patients in China. Here are the key highlights of the study:•The aim of this study was to examine the effects of patient-centered communication, patient participation, and patient preference on patient trust in the context of China.•The research involved a cross-sectional survey of 217 cancer patients in China. The study used mediation and moderation analyses to understand the relationships between patient-centered communication, patient participation, and patient trust. The results show:•First, patient-centered communication increased patient participation in decision-making, which, in turn, enhanced patient trust. Second, patient-centered communication did not have a direct effect on patient trust. Third, patient preference for a passive role in decision-making weakened the relationship between patient participation and patient trust.•The results underscore the significant effect of facilitating patient participation in linking patient-centered communication to patient trust. However, medical communication should also respond to patients’ preferred roles in the decision-making process.•The findings highlight the significant role of patient participation in bridging the gap between patient-centered communication and patient trust. It indicates that doctors should provide patients with opportunities to ask questions and express their concerns. In addition, they should evaluate patients’ preferred degree of involvement before inviting them to contribute so as to respect their preferences and values.