Review on metal ion recognition by bis-rhodamine probes with a future in artificial intelligence and machine learning

Rhodamine probes are highly explored as a host for metal ion recognition. Indeed, along with a single rhodamine unit, bis-rhodamine units are also exploited for the same. Single rhodamine probes are exhaustively studied, whereas bis-rhodamine probes comparatively are younger and less explored, eventually never reviewed separately. Still, bis rhodamine probes have the potential to be individually treated due to multiple reasons such as possibilities of higher sensitivity, better chelation, multi-ion sensing etc. Thus, this review discusses the possibilities of bis-rhodamine probes and possible connections with artificial intelligence and machine learning (AIML) based methods. Several reputed researchers use AI-ML-based methods for multiple uses to fulfil unmet needs. In the case of chemosensors, no such AI-ML-based methods have been reported before. Through this review, the possibility of a promising connection is suggested for chemosensors, particularly bis-rhodamine probes.