Remedial effects of tilapia skin peptides against dexamethasone-induced muscle atrophy in mice by modulation of AKT/FOXO3a and Sirt1/PGC-1α signaling pathways

Cuixian Lin,Jian Zeng,Shilin Zhang, Xiaolan Xu,Lang Chen,Zhiyou Yang,Wenjin Wu,Chuanyin Hu,Yun-Tao Zhao

Journal of Functional Foods（2024）

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摘要

•TSP provides protection against DEX-induced muscle atrophy.•TSP inhibits the expression of ubiquitin protease system.•TSP regulates the Sirt1/PGC-1 and AKT/FOXO3a signaling pathways.

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关键词

Tilapia skin peptides,Dexamethasone,Muscle atrophy,AKT/FOXO3a,Sirt1/PGC-1α

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