Diagnostic and Therapeutic Aptamers: A Promising Pathway to Improved Cardiovascular Disease Management

•Aptamers, like monoclonal antibodies, have a unique structure that allows them to bind to their targets with high specificity and selectivity.•Aptamers are small and flexible synthetic molecules with little steric hindrance and scarcely immunogenic.•Aptamer-based drugs encompass a diverse range of technologies, including novel shapes, chemistries, and delivery methods, as well as an assorted use for therapeutic and diagnostic purposes.•Aptamers have the potential to complement and improve the management of CVDs.