Multiparametric MRI model to predict molecular subtypes of breast cancer using Shapley additive explanations interpretability analysis

Diagnostic and Interventional Imaging(2024)

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摘要
•Lower iAUC, higher kurtosis, lower D*, and lower kurtosis are characteristic of luminal A, luminal B, triple-negative breast cancer, and HER2-enriched breast cancer subtypes, respectively.•Multiparametric model outperforms semantic model in accurately predicting the molecular subtypes of breast cancer.•SHapley Additive exPlanations (SHAP) analysis can enhance the transparency and usability of the model for predicting molecular subtypes of breast cancer.
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关键词
Breast neoplasms,Interpretability analysis,Magnetic resonance imaging,Molecular subtypes,Multiparametric imaging
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