HER2-Mutant Advanced and/or Metastatic Non–Small Cell Lung Cancer: a US Electronic Health Records Database Analysis of Clinical Characteristics, Treatment Practice Patterns, and Outcomes

Sarah Waliany,Joel W. Neal,Nicole Engel-Nitz, Clara Lam, Feng Lin, Leah Park,Lisa Le,Misako Nagasaka

Clinical Lung Cancer（2024）

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摘要

•Patients with HER2-mutant advanced/metastatic NSCLC used a wide range of therapies.•Duration of treatment across lines of therapy was modest.•HER2-directed therapy was infrequently used in early lines of treatment before 2021.

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关键词

Chemotherapy,electronic health record,human epidermal growth factor 2 (HER2),monoclonal antibodies,non-small cell lung cancer (NSCLC),real-world evidence,targeted mutations

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