Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

Biosafety and Health(2023)

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摘要
Employing a comprehensive workflow that incorporates both cellular and molecular viral infection inhibition assays, we screened 167 extracts derived from medicinal fungi for their potential anti-COVID-19 (coronavirus disease 2019) activity. The active compounds, identified as polysaccharides, were characterized using an array of molecular separation techniques and mass spectrometry
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关键词
COVID-19,SARS-CoV-1,SARS-CoV-2,SEC,IEX,MALDI-TOF,MS
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