New piperidinyl heterocyclic azoles acquired through Li(I)-catalyzed reactions: Anti-enzymatic, ADME and computational studies

•Combination and synthesis of nitrogen containing heterocyclic rings.•Heterocyclic analogues as highly potent Urease inhibitors, moderately potent AChE & BChE inhibitors and moderately active antibacterial agents (Biofilm formation).•Enzyme active site binding (Molecular docking).•Drug-likeness (ADMET).•Low toxicity (Hemolytic analysis).