Complete Characterization of RNA Biomarker Fingerprints Using a Multi-Modal ATR-FTIR and SERS Approach for Label-Free Early Breast Cancer Diagnosis.

Shuyan Zhang,Steve Qing Yang Wu,Melissa Hum,Jayakumar Perumal,Ern Yu Tan,Ann Siew Gek Lee,Jinghua Teng,U. S. Dinish,Malini Olivo

RSC Advances（2024）

ASTAR

Cited 4|Views20

Abstract

With the multi-modal approach combining ATR-FTIR and SERS, we achieved an extended spectral range for molecular fingerprint detection of RNA biomarkers. Machine learning results shows 91.6% blind test accuracy for label-free breast cancer diagnosis.

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Key words

Coherent Anti-Stokes Raman Scattering Microscopy,Cancer Detection

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