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Dose-dependent Reduction of Somatic Expansions but Not Htt Aggregates by Di-Valent Sirna-Mediated Silencing of MSH3 in HdhQ111 Mice

Rachelle Driscoll, Lucas Hampton,Neeta A. Abraham, J. Douglas Larigan, Nadine F. Joseph, Juan C. Hernandez-Vega, Sarah Geisler, Fu-Chia Yang, Matthew Deninger,David T. Tran, Natasha Khatri,Bruno M. D. C. Godinho, Garth A. Kinberger, Daniel R. Montagna,Warren D. Hirst, Catherine L. Guardado,Kelly E. Glajch,H. Moore Arnold, Corrie L. Gallant-Behm,Andreas Weihofen

Scientific Reports(2024)

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