Toward understanding the role of the interstitial tissue architects: Possible functions of telocytes in the male gonad

THERIOGENOLOGY(2024)

引用 0|浏览1
暂无评分
摘要
Telocytes represent a relatively recently discovered population of interstitial cells with a unique morphological structure that distinguishes them from other neighboring cells. Through their long protrusions extending from the cell body, telocytes create microenvironments via tissue compartmentalization and create homo- and heterocellular junctions. These establish a three-dimensional network enabling the maintenance of interstitial compartment homeostasis through regulation of extracellular matrix organization and activity, structural support, paracrine and juxtracrine communication, immunomodulation, immune surveillance, cell survival, and apoptosis. The presence of telocytes has also been confirmed in testicular interstitial tissue of many species of animals. The objective of this review is to summarize recent findings on telocytes in the male gonad, on which conclusions have been deduced that indicate the involvement of telocytes in maintaining the cytoarchitecture of the testicular interstitial tissue, in the processes of spermatogenesis and steroidogenesis, and photoperiodmediated changes in the testes in seasonally reproductive animals.
更多
查看译文
关键词
Telocyte,Testes,Interstitial tissue,Steroidogenesis,Spermatogenesis,Seasonal breeding,Bank vole,Mouse,Rat
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要