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Development of Potent and Selective ULK1/2 Inhibitors Based on 7-Azaindole Scaffold with Favorable in Vivo Properties

Alisa Morozova,Sean Chin Chan,Simon Bayle,Luxin Sun,Dylan Grassie, Anna Iermolaieva, Mahalakshmi N. Kalaga,Sylvia Frydman,Samer Sansil,Ernst Scho,Derek Duckett,Andrii Monastyrskyi

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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关键词
ULK1/2 kinase,Autophagy,KRAS,Non -small cell lung cancer,7-Azaindole
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