Circulating miR-423-5p levels are associated with carotid atherosclerosis in patients with chronic kidney disease

Yuzhi Huang,Xueying Feng,Heze Fan, Jian Luo,Zihao Wang,Yuxuan Yang, Wenbo Yang, Wenjiao Zhang,Juan Zhou,Zuyi Yuan, Ying Xiong

Nutrition, metabolism, and cardiovascular diseases : NMCD（2023）

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摘要

•Carotid plaque is one significant factor for the risk of stroke in CKD patients.•Circulating miR-423-5p is a novel biomarker of CKD-associated carotid plaque.•miR-423-5p regulates oxidative stress pathway in the aorta of mice with CKD.

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关键词

miR-423-5p,CKD,Carotid plaque,Oxidative stress

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