A novel end-to-end deep convolutional neural network based skin lesion classification framework

Background: Skin diseases are reported to contribute 1.79% of the global burden of disease. The accurate diagnosis of specific skin diseases is known to be a challenging task due, in part, to variations in skin tone, texture, body hair, etc. Classification of skin lesions using machine learning is a demanding task, due to the varying shapes, sizes, colors, and vague boundaries of some lesions. The use of deep learning for the classification of skin lesion images has been shown to help diagnose the disease at its early stages. Recent studies have demonstrated that these models perform well in skin detection tasks, with high accuracy and efficiency. Objective: Our paper proposes an end -to -end framework for skin lesion classification, and our contributions are two -fold. Firstly, two fundamentally different algorithms are proposed for segmenting and extracting features from images during image preprocessing. Secondly, we present a deep convolutional neural network model, S-MobileNet that aims to classify 7 different types of skin lesions. Methods: We used the HAM10000 dataset, which consists of 10000 dermatoscopic images from different populations and is publicly available through the International Skin Imaging Collaboration (ISIC) Archive. The image data was preprocessed to make it suitable for modeling. Exploratory data analysis (EDA) was performed to understand various attributes and their relationships within the dataset. A modified version of a Gaussian filtering algorithm and SFTA was applied for image segmentation and feature extraction. The processed dataset was then fed into the S-MobileNet model. This model was designed to be lightweight and was analyzed in three dimensions: using the Relu Activation function, the Mish activation function, and applying compression at intermediary layers. In addition, an alternative approach for compressing layers in the S-MobileNet architecture was applied to ensure a lightweight model that does not compromise on performance. Results: The model was trained using several experiments and assessed using various performance measures, including, loss, accuracy, precision, and the F1 -score. Our results demonstrate an improvement in model performance when applying a preprocessing technique. The Mish activation function was shown to outperform Relu. Further, the classification accuracy of the compressed S-MobileNet was shown to outperform S-MobileNet. Conclusions: To conclude, our findings have shown that our proposed deep learning -based S-MobileNet model is the optimal approach for classifying skin lesion images in the HAM10000 dataset. In the future, our approach could be adapted and applied to other datasets, and validated to develop a skin lesion framework that can be utilized in real-time.