Antipyretic effect of inhaled Tetrastigma hemsleyanum polysaccharide on substance and energy metabolism in yeast-induced pyrexia mice via TLR4/NF-κb signaling pathway

Siyu Fu,Xiaodan Bao, Zhejiong Wang, Youying Tang,Qian Wu,Bingqi Zhu,Fangmei Zhou,Zhishan Ding

Journal of ethnopharmacology（2024）

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摘要

Mechanism of the antipyretic activity of THP. THP regulates the TLR4/NF-κB signaling pathway to achieve an antipyretic role through the central nervous system to reduce cytokine levels, histopathological damage and then mediates the endocrine system, substance metabolism and energy metabolism. The figure was created with BioRender.com (accessed on July 10, 2023).Image 1

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关键词

Antipyretic,Metabolism,Polysaccharide,Tetrastigma hemsleyanum,Aerosol,TLR4/NF-κB signaling pathway

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