GM-CSF in Allogenic Hematopoietic Stem Cell Transplantation: from Graft-versus-Host Disease to Graft-versus-Tumor effect.

Chiara Bernardi,Celine Charvet,Robert Zeiser,Federico Simonetta

Transplantation and Cellular Therapy（2024）

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摘要

•GM-CSF plays a major role in acute gastrointestinal (GI)-GvHD development.•Low-dose GM-CSF exerts an immuno-modulatory action in GvHD.•GM-CSF is dispensable for the GvT effect.

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关键词

Granulocyte-Macrophage Colony Stimulating Factor,GM-CSF,GVHD,GvT,Allo-HSCT,cytokines

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