Self-healing dicalcium phosphate dihydrate coating of biomedical magnesium and its in vitro biocompatibility evaluation

MATERIALS LETTERS(2024)

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摘要
To improve the corrosion resistance and biocompatibility of magnesium (Mg) for biomedical applications, a novel coating comprising self -healing dicalcium phosphate dihydrate (DCPD) was applied to Mg using a simple deposition method, without the need for the addition of corrosion inhibitors. Scratch and immersion tests demonstrated that the prepared coating displayed impressive self -healing capabilities, with artificial scratches within 4 h when exposed to 0.9 wt% NaCl solution. The electrochemical test suggested that the DCPD-coating, whether scratched or not, provided effective corrosion protection for the Mg substrate. In vitro cell culture results revealed that the DCPD-coated samples exhibited superior biocompatibility compared to pure Mg. This work offers a new perspective on designing self -healing coatings for Mg, eliminating the need for additional corrosion inhibitors.
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关键词
Biomaterials,Corrosion,Coating,Magnesium,Self-healing
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