Nasal lavage microbiome, but not nasal swab microbiome, correlates with sinonasal inflammation in children with cystic fibrosis

Jaehi Chung,Sébastien Boutin,Dario L. Frey,Cornelia Joachim,Marcus A. Mall,Olaf Sommerburg

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society（2024）

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摘要

•α-diversity and evenness were higher in nasal lavage compared to nose swabs.•Only microbiome in nasal lavage correlated with upper airway inflammation.•Abundance of Moraxella was associated with higher inflammation in the upper airways.

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关键词

Cystic fibrosis,Microbiome,Inflammation,Nasal lavage,Nasal swabs

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