Radical-mediated [3+2+1] annulation of α-polyfluoromethyl-alkenes with arylisocyanates enabled by C(sp3)-F activation

Direct C(sp3)-F functionalization represents an attractively powerful technology for further modification to construct diverse value-added fluorinated structures and enable environmentally persistent fluorinated molecule degradation. However, direct C(sp3)-F activation of alkenyl-CF3...