Comparative Effectiveness of Neoadjuvant Pembrolizumab Versus Cisplatin-based Chemotherapy or Upfront Radical Cystectomy in Patients with Muscle-invasive Urothelial Bladder Cancer

European urology oncology(2024)

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摘要
Improved survival and pathologic response were seen in patients receiving immunotherapy and radical cystectomy for muscle-invasive bladder cancer compared with standard-of-care treatments. Randomized controlled trials are needed to further validate these findings in both the cisplatin-eligible and the cisplatin-ineligible populations.
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关键词
Muscle-invasive bladder cancer,Pembrolizumab,Neoadjuvant chemotherapy,Radical cystectomy,Outcome analysis
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