Circulating biomarkers of the CS4P and CLIP scores are not altered in a pig model of acute cardiogenic shock and additional short-term circulatory support

Christian Riehle,Jan-Thorben Sieweke,Nanna Louise Junker Udesen,Ole K.L. Helgestad,Natali Froese,Hanne Berg Ravn,Ralf Lichtinghagen,Jacob E. Møller,Johann Bauersachs,Andreas Schäfer

International Journal of Cardiology（2024）

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摘要

•We utilize a porcine model of cardiogenic shock (CS) and percutaneous left ventricular (LV) unloading.•Recently, the CS4P and CLIP scores have been developed to predict survival in CS patients.•Acute CS and additional LV unloading have no impact on circulating biomarkers of the CS4P and CLIP scores in our model.•The CS4P and CLIP scores do not reflect whole-body dysregulation in acute CS and additional LV unloading in our model.

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关键词

Cardiogenic shock,Circulating biomarkers,Mechanical unloading,Myocardial infarction

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