Inferring Incidence of Unreported SARS-CoV-2 Infections Using Seroprevalence of Open Reading Frame 8 Antigen, Hong Kong.

Shi Zhao,Chris Ka Pun Mok, Yun Sang Tang,Chunke Chen,Yuanxin Sun,Ka Chun Chong,David S C Hui

Emerging infectious diseases（2024）

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摘要

We tested seroprevalence of open reading frame 8 antigens to infer the number of unrecognized SARS-CoV-2 Omicron infections in Hong Kong during 2022. We estimate 33.6% of the population was infected, 72.1% asymptomatically. Surveillance and control activities during large-scale outbreaks should account for potentially substantial undercounts.

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关键词

COVID-19,viruses,SARS-CoV-2 Omicron variant,ORF8 antigen,infection attack rate,respiratory infections

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