DCAF1-based PROTACs with Activity Against Clinically Validated Targets Overcoming Intrinsic- and Acquired-Degrader Resistance
Martin Schröder,Martin Renatus,Xiaoyou Liang,Fabian Meili,Thomas Zoller,Sandrine Ferrand, Francois Gauter,Xiaoyan Li,Frederic Sigoillot,Scott Gleim,Therese-Marie Stachyra,Jason R. Thomas,Damien Begue,Maryam Khoshouei, Peggy Lefeuvre,Rita Andraos-Rey, BoYee Chung,Renate Ma,Benika Pinch,Andreas Hofmann,Markus Schirle,Niko Schmiedeberg,Patricia Imbach,Delphine Gorses,Keith Calkins,Beatrice Bauer-Probst,Magdalena Maschlej, Matt Niederst,Rob Maher,Martin Henault,John Alford,Erik Ahrne,Luca Tordella, Greg Hollingworth,Nicolas H. Thomä,Anna Vulpetti,Thomas Radimerski,Philipp Holzer,Seth Carbonneau,Claudio R. Thoma NATURE COMMUNICATIONS（2024）
关键词
Protein Degradation,PROTACs
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