En bloc resection of an extremely giant mediastinal immature teratoma with somatic-type malignancy: A case report with a brief review of the literature

Primary mediastinum immature teratoma with somatic-type malignant transformation (SM) is extremely rare, and the clinical prognosis is poor. Immature teratoma with SM is difficult to eradicate by chemotherapy due to poor sensitivity; therefore, surgical resection is recommended whenever possible because it may offer better survival. A large mass (approximately 21.6 x 12.3 x 105 cm3) in the anterior mediastinum with a well-defined margin and the important structures in the mediastinum were compressed and surrounded by the tumor. Then the en bloc resection of the large solid tumor with an intact capsule via a median sternotomy was conducted.image