Power-engine-load form for dynamic absolute concentration robustness

SIAM JOURNAL ON APPLIED MATHEMATICS(2023)

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摘要
In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical network with output robustness and therefore is essential for its functioning in a highly variable environment. It is important to identify the structure of the dynamical system as well as the constraints required for dynamic ACR. We propose a power-engine-load form of dynamic ACR and obtain results regarding convergence to the ACR value based on this form.
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关键词
Key words. biochemical reaction network,absolute concentration robustness,power-engine-load form,chemostat,robust output
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