Nuclear Cross-Section of Proton-Induced Reactions on Enriched 48Ti Targets for the Production of Theranostic 47Sc Radionuclide, 46cSc, 44mSc, 44gSc, 43Sc, and 48V

Liliana Mou, Lucia De Dominicis,Sara Cisternino, Hanna Skliarova,Matteo Campostrini, Valentino Rigato,Laura De Nardo,Laura Melendez-Alafort, Juan Esposito,Ferid Haddad,Gaia Pupillo

PHARMACEUTICALS(2024)

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摘要
The cross-sections of the Ti-48(p,x)Sc-47, Sc-46c, Sc-44m, Sc-44g, Sc-43, and V-48 nuclear reactions were measured from 18 to 70 MeV, with particular attention to Sc-47 production. Enriched Ti-48 powder was deposited on an aluminum backing and the obtained targets were characterized via elastic backscattering spectroscopy at the INFN-LNL. Targets were exposed to low-intensity proton irradiation using the stacked-foils technique at the ARRONAX facility. Activated samples were measured using gamma-spectrometry; the results were compared with the data int he literature and the theoretical TALYS-based values. A regular trend in the new values obtained from the different irradiation runs was noted, as well as a good agreement with the literature data, for all the radionuclides of interest: Sc-47, Sc-46c, Sc-44m, Sc-44g, Sc-43, and V-48. Sc-47 production was also discussed, considering yield and radionuclidic purity, for different Sc-47 production scenarios.
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关键词
Sc-47,Ti-48 targets,cross-section measurements,proton cyclotron,nuclear reactions
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