Approximation of Hodgkin-Huxley Model Using Neural Networks.

Simulation of electrophysiological cardiac models plays a critical role in enabling researchers to investigate the heart’s activity under various conditions. In this domain, the cell model assumes a significant position, as its accuracy and complexity have a direct impact on the reliability of simulation outcomes. Presently, most cell models are grounded in the Hodgkin-Huxley theory. However, some of these models prove sensitive to the initial values or time steps utilized in solving ordinary differential equations (ODEs). With the rapid advancements in deep learning, the application of this technology has expanded beyond image processing. In this paper, we propose a novel method to construct a cell model based on a neural network. Through experiments, we demonstrate that our new model exhibits high accuracy and robustness when compared to traditional cell models. The results validate the potential of employing deep learning techniques to enhance the reliability and performance of cardiac simulations, opening new avenues for future research in this domain.