Antibiofilm activity of biosurfactant produced by a sponge-associated marine Cobetia sp. JCG-23

Marine symbiotically associated microbes play a vital role and are an excellent source of natural compounds that exert wide biological activities. In this study, we have reported on the identification, characterization, phylogenetic relationship, and anti-biofilm surface-active compound-producing abilities of marine invertebrate sponge-associated Cobetia sp. JCG-23. Among 24 isolates, a total of five strains (JCG2, JCG19, JCG20, JCG22, and JCG23) have active surface molecule producing potential on the emulsification index assay. Interestingly, the potential candidate JCG-23, produces biosurfactants with low surface tension (22 Nm-1) that exert anti-biofilm activity against Pseudomonas aeruginosa PAO1. The isolate was identified as genus Cobetia sp. JCG-23 with 99.1